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Table 1 List of top 50 up regulated genes (sorted by PMA 24 hrs)

From: Identification of novel transcriptional regulators involved in macrophage differentiation and activation in U937 cells

  

Illumina array fold change

Ref.Seq.

Gene Symbol

PMA6

PMA12

PMA24

PMA32

LPS

VitD3

NM_014220

HL6

20.6

88.5

96.3

96.5

128.2

1.1

NM_005368

MB

4.3

27.8

90.5

110.5

96.2

7.7

NM_000582

BNSP

7.6

31.1

84.1

118.1

110.9

1

NM_021796

PLAC1

1.8

11.8

34.6

39.1

34.3

-1.1

NM_002423

MMP7

1.9

2.7

29.9

61.4

36.5

-1.4

NM_002922

RGS1

15.9

25.6

28.6

26

29.9

-1.1

NM_018993

RIN2

9.5

18.2

23.2

18.9

14.4

1

NM_001955

EDN1

42.9

22.9

21.2

22.9

85.4

1

NM_000265

NCF1

3.4

11.2

18.6

21

17.8

3.8

NM_001332

CTNND2

1.5

4.9

15.7

20.4

12.8

1.1

NM_016270

KLF2

15.5

11.6

13.9

15.2

9.8

-1.3

NM_002167

ID3

1.8

3.4

11.9

6.2

38.9

2.7

NM_002203

CD49B

2

7

10.5

9.3

6.9

1

NM_000014

A2M

4.1

7.4

10.4

11.1

11.5

1.1

NM_001401

EDG2

4.4

9.2

10.3

8.8

6.6

-1.8

NM_152591

CCDC63

2.5

7.1

9.9

9.8

10.6

-1.1

NM_030820

COL20A1

1.2

2.8

8.8

7.7

7.4

-1.1

NM_004994

MMP9

2.4

6

8.4

10.1

8.3

-1.2

NM_004926

BERG36

6.5

8.1

8.2

7.7

9.9

-1.4

NM_001200

BMP2

15.2

13.6

8.1

4.1

10.3

-1.2

NM_015271

RNF86

2.6

5.5

8.1

10

7

-1

NM_021952

ELAVL4

7.3

8.1

8

7.9

6.8

-1.1

NM_001706

BCL6

7.1

8.3

7.6

7.6

19.5

1.6

NM_001565

CXCL10

1.4

1.5

7.5

12.6

23.4

-1

NM_005627

SGK

3.4

4.9

7.5

6.6

13

-1

NM_007351

ECM

3.3

7.2

7.3

8.4

8

1.1

NM_206827

RASL11A

1.2

4.3

7.2

6

4.5

1.2

NM_002983

CCL3

8.9

8.9

7.1

8.2

197.3

1.4

NM_003294

ALPHAII

2.4

4.6

7.1

9.4

8.6

1.1

NM_153370

PI16

1

1.6

6.9

10.3

6.9

1

NM_003986

BBH

1.7

3

6.8

9.8

6.6

-1.2

NM_025113

C13ORF18

2.5

4.7

6.7

5.3

14.8

1.3

NM_005449

TOSO

3.7

8.4

6.4

6

7

1.4

NM_000389

P21

2.4

4.2

6.1

6.1

11.8

1.3

NM_001001437

CCL3L3

8.5

7.8

6

6.1

187

1.2

NM_001268

CHC1L

1.6

3.4

6

6.8

4.7

1.1

NM_206939

CD20L4

-1.2

2.8

5.9

8.3

6.9

-2

NM_004615

A15

1.2

3.5

5.8

6.3

4.8

-1.3

NM_016134

PGCP

1.4

3

5.7

7.1

5.4

-1.1

NM_005211

CD115

2.2

5.6

5.6

4.8

5.1

1.7

NM_147130

LY117

2.8

5.3

5.6

4.5

5.3

1.2

NM_013445

GAD

1.1

3.9

5.6

5.9

5

-1.2

NM_007079

PRL3

1.6

3.9

5.6

7.9

7.1

-1.2

NM_032199

ARID5B

7

5

5.5

5.7

6.6

-2.1

NM_001257

CDH13

1

2.7

5.5

5.6

5.1

-1.2

NM_001017998

GNG10

2

4.3

5.5

7.4

5.3

1.5

NM_005842

HSPRY2

4.3

5.8

5.4

5.2

4.1

-1

NM_016257

HLP4

1.2

2.7

5.4

7

5.3

1.2

NM_052815

DIF2

6.8

5.1

5.3

4.7

157.7

1.1

NM_014862

ARNT2

2.5

5.4

5.3

4.8

5.3

-1

  1. The column designation indicates different time points of differentiation with PMA (6 hrs, 12 hrs, 24 hrs and 32 hrs), VitD3 (24 hrs) and subsequent activation of PMA differentiated cells (24 hrs) by LPS (2 hrs). The numbers denote fold change after normalization of Illumina array data. The order of genes was sorted by PMA 24 hrs sample in descendent manner.
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BMC Immunology

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