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Table 1 Cytokine production of stimulated splenocytes

From: CD8+ T cell activation predominate early immune responses to hypercholesterolemia in Apoe-/- mice

 

IFN-γ (pg/ml)

IL-4 (pg/ml)

IL-10 (pg/ml)

 

Chow

HFD

Chow

HFD

Chow

HFD

4 weeks

620.8 ± 395.9

898.6 ± 784.3

8.5 ± 2.9

13.0 ± 3.4

83.3 ± 49.0

95.8 ± 80.0

P

n.s

**

n.s

8 weeks

1052.0 ± 803.8

574.6 ± 382.5

8.3 ± 2.8

8.8 ± 2.4

75.6 ± 28.9

82.7 ± 43.5

P

n.s

n.s

n.s

  1. Concentration of IL-4, IL-10 and IFN-γ in cell supernatant of conA stimulated splenocytes from mice fed chow or high fat diet for 4 or 8 weeks. **P < 0.01.