Skip to main content

Table 1 Phenotype of splenic lymphocytes, thymocytes and lymph node cells (as percent CD4+ and CD8+ gated) harvested from DC-vaccinated and control mice after 7 days of first immunization.

From: In vivo trafficking and immunostimulatory potential of an intranasally-administered primary dendritic cell-based vaccine

Cells→

Groups ↓

CD4+

CD8+

 

CD25+

CD69+/- activated T cells

CD44+ resting memory

TEM

CCR-

CD62L hi(lo)

TCM

CCR+ CD62L hi

CD25+

CD69+/- activated T cells

CD44+ resting memory

TEM

CCR- CD62L lo

TCM

CCR+

CD62L hi

Spleen

        

DC vaccinated

0.88

87.3

39.9(56)

3.5

99.9

88.5

27.4

6.8

Control

1.27

92.6

56(38.2)

6.0

100

83.3

20.1

9.8

Thymocytes

        

DC vaccinated

15.9

85.7

27.4(71)

0.51

100

53.8

69.3

3.5

Control

18.9

86.1

26.4(72)

0.53

100

56.8

69

3.7

Lymph node

        

DC vaccinated

1.72

88

64(33)

2.3

100

72.2

34.2

3.2

Control

1.51

90.2

67(29)

3.2

100

74.4

32

3.9

  1. Results are from one representative experiment (n = 5 mice per group) performed thrice.