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Figure 1 | BMC Immunology

Figure 1

From: Differential utilization of NF-kappaB RELA and RELB in response to extracellular versus intracellular polyIC stimulation in HT1080 cells

Figure 1

Extracellular and intracellular polyIC treatments induce genes with different kinetic and magnitude. HT1080 cell line was treated with 40 μg/ml ex-polyIC (open square) and 0.4 μg/ml in-polyIC (closed square) for 0 to 12 hours. Gene expression was measured using qPCR and the mean from triplicate experiments was calculated. Error bars represent standard error. A. IFNB, TNF and IL8 inductions in response to extracellular and intracellular polyIC treatments have both different kinetic and magnitude. B. IL6 and CCL2 inductions in response to extracellular and intracellular polyIC treatments have similar magnitude but different kinetic. C. CCL3 inductions in response to extracellular and intracellular polyIC treatments have similar kinetic but different magnitude.

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