Table 2 Four single nucleotide polymorphisms in the STAT6 gene in 265 HCV-1 and 195 HCV-2 infected patients receiving PEG-IFNα-RBV therapy with or without a SVR in a Chinese population in Taiwan
From: The impact of polymorphisms in STAT6 on treatment outcome in HCV infected Taiwanese Chinese
SNPs | Position in STAT6 | Chromosome positiona | Alleles (1/2) | HCV-1 | HCV-2 | ||||
|---|---|---|---|---|---|---|---|---|---|
HWE (P value) | MAF | HWE (P value) | MAF | ||||||
SVR (+) | SVR (−) | SVR (+) | SVR (−) | ||||||
rs1059513 (S1) | 3′ UTR | 57489709 | A/G | 0.3808 | 0.0982 | 0.0441 | 1 | 0.0646 | 0.0589 |
rs703817 (S2) | 3′ UTR | 57489828 | A/G | 0.7565 | 0.2454 | 0.3119 | 0.7054 | 0.2612 | 0.1471 |
rs324015 (S3) | 3′ UTR | 57490100 | A/G | 0.5347 | 0.4448 | 0.4406 | 0.5655 | 0.4831 | 0.4118 |
rs3024974 (S4) | Intron 17 (boundary) | 57492745 | C/T | 0.8524 | 0.2086 | 0.2108 | 0.6503 | 0.1949 | 0.2059 |