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Table 2 TCR Vβ repertoire usage by age groups

From: Flow cytometric analysis of the CD4+ TCR Vβ repertoire in the peripheral blood of children with type 1 diabetes mellitus, systemic lupus erythematosus and age-matched healthy controls

Vβ repertoire usage

Age categories

   

18 months-4 years

 

5-9 years

 

10-14 years

 

Total

 
 

Median

IQR*

p(18 m-4/5-9)†

Median

IQR*

p(5-9/10-14)

Median

IQR*

p(18 m-4/10-14)

Median

IQR*

p(overall)

Vβ3

4.70

3.10

.080

3.35

2.90

.121

5.20

2.60

.831

4.40

3.60

.156

Vβ5.3

1.50

.70

.692

1.35

.90

.033

2.30

.90

.059

1.60

1.10

.068

Vβ7.1

1.50

.85

.643

1.25

.90

.022

2.60

1.20

.050

1.60

1.50

.048

Vβ16

1.70

1.10

.972

2.10

1.00

.248

2.50

1.40

.319

1.95

1.40

.472

Vβ9

2.35

1.30

.915

2.70

1.60

.825

2.60

1.40

.943

2.50

1.40

.984

Vβ17

4.05

1.85

.695

3.90

1.70

.690

4.30

1.80

.337

4.20

1.70

.652

Vβ20

3.35

1.70

.339

4.10

3.10

.838

5.10

2.30

.145

3.80

3.00

.346

Vβ18

.85

.90

.427

1.15

.80

.093

2.10

1.20

.027

1.20

1.50

.063

Vβ5.1

3.85

1.65

.448

4.85

3.00

.935

4.00

2.80

.670

4.20

2.30

.767

Vβ8

4.00

1.30

.741

4.00

1.80

.236

3.70

1.40

.374

3.90

1.60

.472

Vβ13.1

3.90

1.30

.692

3.75

2.10

.595

4.20

1.10

.859

3.90

1.50

.856

Vβ13.6

1.55

.60

.128

1.85

.70

.594

2.10

.50

.058

1.80

.80

.116

Vβ12

4.70

1.65

.717

4.50

2.10

.462

4.20

2.50

.125

4.50

1.80

.367

Vβ5.2

1.05

.90

.643

1.10

.50

.712

1.20

.90

.617

1.10

.90

.824

Vβ2

7.90

3.25

.448

6.95

3.80

.513

7.60

3.10

.722

7.40

3.70

.688

Vβ21.3

2.35

.95

.222

2.65

1.00

.967

2.80

.70

.319

2.60

1.00

.418

Vβ23

.80

.65

.740

.75

1.10

.189

1.30

1.50

.074

.80

1.10

.188

Vβ1

3.10

.55

.425

3.25

.70

.594

3.50

1.10

.198

3.10

.80

.414

Vβ14

4.20

1.75

.306

3.50

1.90

.967

3.70

1.50

.226

3.70

2.00

.418

Vβ11

1.20

.95

.921

1.50

.90

.190

1.80

1.40

.212

1.40

1.00

.342

Vβ22

2.70

1.20

.766

2.55

1.10

.165

3.10

1.40

.269

2.70

1.10

.348

Vβ7.2

1.35

1.70

.113

2.25

1.90

.487

1.70

1.10

.355

1.70

1.70

.261

Vβ13.2

1.85

.95

.129

2.80

1.80

1.000

2.40

.30

.042

2.20

1.50

.110

Vβ4

.85

.65

.741

.70

.70

.411

.50

.90

.238

.70

.80

.484

  1. No age-related differences in CD4 + Vβ expression were found among the three age groups of healthy Greek children studied.
  2. * IQR Interquartile range (75th - 25th percentile).
  3. † The numbers in brackets indicate the two age groups that were used for the comparison with the corresponding p-value.
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BMC Immunology

ISSN: 1471-2172

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