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Table 6 Logistic regression analysis of IgG subclasses in relation to the risk of early onset sepsis compared with suspected patients

From: Neonatal infections in Saudi Arabia: association with C-reactive protein, CRP -286 (C>T>A) gene polymorphism and IgG antibodies

Antibody isotopes

Categorized IgG subclasses levels

OR (95% CI)

P value

IgG

Lower level

1.00

 

Medium level

0.69 (0.29–1.62)

0.394

Higher level

0.213 (0.09–0.51)

<0.001

IgG1

Lower level

1.00

 

Medium level

1.34 (0.51–3.50)

0.558

Higher level

0.30 (0.12–0.76)

0.011

IgG2

Lower level

1.00

 

Medium level

0.44 (0.37– 0.73)

0.001

Higher level

0.34 (0.20–0.49)

0.030

IgG3

Lower level

1.00

 

Medium level

0.44 (0.18–1.07)

0.070

Higher level

0.32 (0.13–0.75)

0.009

IgG4

Lower level

1.00

 

Medium level

2.82 (1.16–6.90)

0.023

Higher level

1.71 (0.73–4.00)

0.213