Figure 3From: Enhanced immunogenicity of a functional enzyme by T cell epitope modificationSchematic representation of the parent and modified enzyme variant. The first Guinea pig T cell epitope on B. lentus subtilisin has an analogous sequence (with a single amino acid change) in BPN' Y217L which is not detected in our assay as a T-cell epitope. A hybrid BPN' Y217L enzyme (GP002) was designed which contains the B. lentus subtilisin epitope.Back to article page