Figure 8
From: Cloning and characterization of deer mouse (Peromyscus maniculatus) cytokine and chemokine cDNAs
Amino acid alignment of deer mouse (Pema), house mouse (Mus), rat (Rattus) and human (Homo) CCL2. Sequences were aligned as described in Figure 1. The fragment represents 60% of the polypeptide. Conserved secondary structures (underlined) and cysteines are present in deer mouse CCL2. Two highly conserved regions that form the homodimer interface are also conserved in deer mouse CCL2. Rodent CCL2 polypeptides are substantially longer than human CCL2.