Table 1 Physiochemical functionality of peptide side chains.
From: HLA class I supertypes: a revised and updated classification
Pocket specificity | Associated amino acid residues |
|---|---|
Acidic | DE |
Aliphatic | LIVMQ |
Aromatic | FWY |
Aromatic and aliphatic | FWYLIVMQ |
Aromatic and basic | YRK |
Aromatic and large hydrophobic | FWYLIM |
Basic | RHK |
Hydrophobic | LIVMFWYA |
Large hydrophobic | FLIM |
Proline | P |
Small | AST |
Small and aliphatic | ATSVLIMQ |
Small hydrophobic | AV |
Small, aliphatic and aromatic | ASTVLIMQFWY |