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Table 4 Top 10 functional annotations for two merged networks upregulated in response to heat shock (based on p value).

From: Divergence of canonical danger signals: The genome-level expression patterns of human mononuclear cells subjected to heat shock or lipopolysaccharide

Category

Term

# of genes

p-value

SP_PIR_KEYWORDS

chaperone

11

1.4E-8

GOTERM_BP_ALL

protein folding

14

4.6E-7

SP_PIR_KEYWORDS

heat shock

8

1.2E-7

GOTERM_BP_ALL

response to unfolded protein

9

5.4E-7

GOTERM_BP_ALL

response to protein stimulus

9

5.4E-7

SP_PIR_KEYWORDS

nucleotide-binding

22

3.2E-7

SP_PIR_KEYWORDS

molecular chaperone

6

4.4E-7

GOTERM_MF_ALL

unfolded protein binding

11

4.5E-6

SP_PIR_KEYWORDS

atp-binding

18

6.6E-6

INTERPRO_NAME

chaperonin TCP-1

5

3.8E-4

  1. The analysis is based on the default parameters in D.A.V.I.D. and uses Benjamini-Hochberg correction for multiple testing.