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Table 1 Hemodynamic parameters in the mice cremasteric microcirculation

From: Leukotriene B4-loaded microspheres: a new therapeutic strategy to modulate cell activation

 

Saline

LPS

Unloaded MS

LTB4-loaded MS

LTB4 solution

Venular diameter (μm)

26.5 ± 4.7

28.0 ± 3.4

19.5 ± 1.5

17.3 ± 1.2

20.0 ± 2

Venular shear rate (s-1)

618.7 ± 6.2

784.0 ± 1.3

843.8 ± 108.5

670.2 ± 65

879.0 ± 143.7

  1. Parameters (mean ± SEM, in C57BL/6J mice used for intravital microscopy studies) were measured 4 h after the intraescrotal injection of saline, LPS (0.05 μg/kg), unloaded or LTB4-loaded MS (1 mg/ml) and LTB4 solution (200 ng/ml); (n = 4), from two different experiments.