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Figure 3 | BMC Immunology

Figure 3

From: Protection against tuberculosis by a single intranasal administration of DNA-hsp65 vaccine complexed with cationic liposomes

Figure 3

Anti-hsp65 subtype antibody production in mice immunized with liposomes or naked DNA. BALB/c mice were immunized by intramuscular injection with 4 doses of 100 μg of naked DNA or a single dose of 100 μL of liposome (corresponding to 50 μg of DNA). Anti-hsp65 antibody levels were evaluated in mice serum by ELISA 30 days after the last immunization. A) IgG2a and B) IgG1 isotypes. Results are presented by mean ± SD of optical density. *p < 0.05 were considered significant when compared to saline group or their respective controls.

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BMC Immunology

ISSN: 1471-2172

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