Figure 3

Correlation between different immunophenotypes of T _reg with expression of Ki-67. Frequency of CTLA-4⁺, CD127^low, or GITR⁺ T_reg were correlated with proportion of CD4⁺Ki67⁺ T cells in Control (Blue diamond), HTLV (Green triangle) and HAM/TSP (Red circle). A. There was a negative correlation between CTLA-4⁺ T_reg with percentage of CD4⁺Ki67⁺ T cells in HAM/TSP only (r = -0.7833, p = 0.017). B. CD127^low T_reg were inversely correlated with proportion of CD4⁺Ki67⁺ T cells in Control group (r = -0.8108, p = 0.034). C. There was no association between GITR⁺ T_reg with percentage of CD4⁺Ki67⁺ T cells in any group.