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Table 1 Demographics of children with JDM in expression profiling study.

From: Duration of chronic inflammation alters gene expression in muscle from untreated girls with juvenile dermatomyositis

Patient No.

Age at Onset

DAS Skin

DAS Weak

DAS Total

Age at MBx

Duration of Untreated Disease (Months)

DQA 0301

DQA 0501

TNF Type

Short Disease Duration

1

4.7

4.0

7.0

11.0

4.8

1.1

neg

pos

GA

2

6.8

7.0

9.0

16.0

6.8

1.1

neg

pos

GG

3

5.5

4.0

4.0

8.0

5.50

0.6

neg

pos

GA

Mean

5.6

5.0

6.7

11.7

5.7

0.9

   

ST. Dev.

1.0

1.7

2.5

4.0

1.1

0.3

   

Long Disease Duration

4

1.0

6.0

5.5

11.5

3.5

30.6

neg

pos

GA

5

1.8

6.0

3.0

9.0

2.3

6.1

pos

neg

GG

6

8.3

9.0

10.0

19.0

8.5

2.1

neg

neg

GG

7

8.8

5.0

4.0

9.0

9.0

2.6

neg

pos

GA

8

3.9

6.0

9.0

15.0

5.2

16.1

neg

neg

GG

9

1.6

7.0

9.0

16.0

2.2

7.7

pos

neg

GG

10

7.2

8.0

6.0

14.0

7.4

2.2

pos

neg

GG

11

8.3

4.0

8.0

12.0

8.7

4.9

neg

pos

AA

12

6.0

7.0

3.0

10.0

7.7

20.6

pos

pos

GG

13

7.7

6.0

7.0

13.0

8.2

6.4

neg

pos

GG

14

2.5

3.0

1.0

4.0

3.6

13.6

neg

neg

GG

15

2.6

7.0

3.0

10.0

11.3

105.6

neg

neg

GA

16

6.1

7.0

10.0

17.0

6.6

6.6

neg

neg

GA

17

4.5

6.0

6.0

12.0

5.2

8.5

neg

pos

GG

18

5.1

6.0

8.0

14.0

10.3

63.5

neg

pos

AA

19

8.4

6.0

1.0

7.0

8.6

3.2

neg

pos

GG

Mean

5.1

6.2

5.8

12.0

6.7

18.8

   

ST. Dev.

2.8

1.4

3.1

3.9

2.9

27.9

   
  1. DAS: disease activity score; MBx: muscle biopsy; DQA: Major histocompatibility complex, class II, DQ alpha-1; TNF type: Tumor necrosis factor -308 allele.