Figure 5From: Host immunity in the protective response to vaccination with heat-killed Burkholderia malleiTNF-α impact on chronic B. mallei infection. BALB/c mice challenged i.p. with 1 × 106 CFU B. mallei were depleted of TNF-α (n = 6) or antibody control (n = 5) at day 42 post infection. Rapid mortality was observed at 7 days post TNF-α depletion (p = 0.0023).Back to article page