Figure 2From: The prokineticin receptor agonist Bv8 decreases IL-10 and IL-4 production in mice splenocytes by activating prokineticin receptor-1 IL-1 production. Effect of the in vitro addition of Bv8 on IL-1β production by mouse splenocytes in the presence or absence of 10 μg/ml Con-A; IL-1β levels were measured 24 hours later. Results from one typical experiment involving eight mice/group. Mean values ± SD. *p < 0.05 vs CTR (Con-A stimulated cultures without Bv8).Back to article page