Figure 4From: The prokineticin receptor agonist Bv8 decreases IL-10 and IL-4 production in mice splenocytes by activating prokineticin receptor-1 PROKR 1 KO mice. Effect of the in vitro addition of Bv8 (10-9 M) on IL-10 (panel A) and IL-4 production (panel B) by mouse splenocytes from WT and PROKR 1 KO mice. The cells were stimulated in vitro with Con-A for 48 h. Results from experiments involving four mice/group. Mean values ± SD. *p < 0.05 vs Con-A only.Back to article page