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Figure 6 | BMC Immunology

Figure 6

From: The prokineticin receptor agonist Bv8 decreases IL-10 and IL-4 production in mice splenocytes by activating prokineticin receptor-1

Figure 6

KLH immunisation + in vitro Bv8. Effect of in vitro addition of Bv8 (10-9 M) on IL-2 (panel A), IFN-γ (panel B), IL-10 (panel C) and IL-4 production (panel D) by splenocytes of mice immunised with KLH. Two weeks after immunisation, the splenocytes were cultured in the presence or absence of 80 μg/ml KLH for 48 h (IL-2 and IFN-γ) or 72 h (IL-10 and IL-4). Results from one typical experiment involving eight mice/group. Mean values ± SD. *p < 0.05 vs KLH-stimulated cultures without Bv8.

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BMC Immunology

ISSN: 1471-2172

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