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Figure 5 | BMC Immunology

Figure 5

From: Insulin-like growth factor I promotes cord blood T cell maturation through monocytes and inhibits their apoptosis in part through interleukin-6

Figure 5

Effects of IGF-1 and IL-6 on PHA-induced apoptosis in purified CB CD3+ T cell culture. CB CD3+ T cells were cultured with (a) PHA (1 μg/mL) ± IGF-1 (100 ng/mL) or (b) PHA (1 μg/mL) ± IL-6 (10 ng/mL) for 4 days. Both IGF-1 and IL-6 significantly inhibited PHA-induced apoptosis in T cell subsets. Results shown are mean ± SEM of 9 and 4 independent cases of CD3+ T cells respectively (* p < 0.05).

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