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Figure 2 | BMC Immunology

Figure 2

From: Defective IL-17- and IL-22-dependent mucosal host response to Candida albicans determines susceptibility to oral candidiasis in mice expressing the HIV-1 transgene

Figure 2

qRT-PCR analysis of signature genes of CD4+ T-cell subsets polarized in vitro . Naive CD4+ precursors were harvested from CD4C/HIVMutA Tg and non-Tg mice, and incubated with subset-specific differentiating cytokines and blocking antibodies. Bars represent the mean ± standard error range of significantly (p < 0.05) up- or down-regulated genes compared to that of control naive cells from non-Tg mice, incubated without cytokines and antibodies. In all differentiating conditions, gene expression of IL-4 and IL-10 was not significantly different (p > 0.05) from control. Data are from 6 independent experiments.

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