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Figure 2 | BMC Immunology

Figure 2

From: RAGE controls leukocyte adhesion in preterm and term infants

Figure 2

RAGE- and ICAM-1-dependent fetal neutrophil adhesion. Neutrophil adhesion of preterm and term infants and adults was analyzed in dynamic microflow chamber experiments (A) Neutrophil adhesion upon P-selectin, IL-8 and ICAM-1 was compared between the various age groups and to respective uncoated controls. (B) Neutrophil adhesion is shown for P-selectin and IL-8 coated flow chambers with and without ICAM-1. (C) ICAM-1-and sRAGE-dependent neutrophil adhesion in combination with P-selectin and IL-8-coating. Results are presented as mean + SEM from at least 5 separate individuals/experiments per group. Significant differences (p <0.05) to uncoated or P-selectin and IL-8 coated flow chambers are indicated by asterisks and by the pound key (as indicated).

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