Skip to main content

Table 5 Fifteen most up regulated genes in SIV/Meth macaques in comparison to SIV

From: Methamphetamine abuse affects gene expression in brain-derived microglia of SIV-infected macaques to enhance inflammation and promote virus targets

Gene

Name

Fold change

P value

AQP9

Aquaporin 9

94.2

0.028

OAS1

2′,5′-oligoadenylate synthetase 1

11.98

0.00005

MAMU-A1

Macaca mulatta Mamu-A MHC class I antigen

5.19

0.038

GPD1

Glycerol-3-phosphate dehydrogenase 1

3.69

0.037

SERPINA1

Serpin peptidase inhibitor, clade A

3.37

0.002

VSIG1

V-set and immunoglobulin domain containing 1

3.1

0.02

NAT2

N-acetyltransferase 2 (arylamine N-acetyltransferase)

2.96

0.026

CD244

Natural killer cell receptor 2B4

2.78

0.031

IRF5

Interferon regulatory factor 5

2.66

0.032

TXNDC2

Thioredoxin domain-containing protein 2-like

2.59

0.028

IL1RAPL1

Interleukin 1 receptor accessory protein-like 1

2.29

0.007

GRIN2B

Glutamate receptor, ionotropic, N-methyl D-aspartate 2B

2.29

0.003

ZSCAN1

Zinc finger and SCAN domain containing 1

2.17

0.023

GPR17

G protein-coupled receptor 17, transcript variant 2

2.13

0.016

HIVEP3

Human immunodeficiency virus type I enhancer binding protein 3

94.21

0.028