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Table 4 Hematopoietic cell reconstitution in spleen

From: Long-term leukocyte reconstitution in NSG mice transplanted with human cord blood hematopoietic stem and progenitor cells

 

16 weeks

24 weeks

32 weeks

CD45+

83.3 ± 9.93%

71.0 ± 18.2%

72.9 ± 20.1%

B cells

78.8 ± 4.42%

53.7 ± 20.5%

43.7 ± 14.7%

  Mature

63.8 ± 3.63%

69.4 ± 12.3%

61.7 ± 11.8%

  Memory

0.53 ± 0.26%

3.12 ± 2.24%

4.86 ± 1.61%

T cells

9.27 ± 2.14%

32.5 ± 18.0%

37.9 ± 19.0%

  CD4 T cells

51.6 ± 8.89%

65.7 ± 12.0%

46.9 ± 8.77%

    Memory

52.7 ± 9.87%

77.1 ± 14.0%

54.7 ± 26.4%

  CD8 T cells

37.8 ± 8.75%

25.4 ± 19.2%

58.4 ± 32.3%

  Memory

24.4 ± 4.71%

59.1 ± 22.8%

34.4 ± 30.8%

NK cells

5.85 ± 1.46%

7.61 ± 1.34%

8.74 ± 1.13%

Monocytes

1.94 ± 1.42%

0.73 ± 0.36%

1.71 ± 0.97%

pDCs

6.79 ± 1.92%

9.71 ± 1.97%

9.83 ± 1.28%

CD1c + mDCs

0.64 ± 0.32%

0.71 ± 0.25%

0.83 ± 0.37%

CD141+ mDCs

0.05 ± 0.02%

0.05 ± 0.06%

0.07 ± 0.01%

  1. Percentages are given as mean ± SD; n = 6 (16 weeks), 8 (week 24), 8 (week 32)