Table 2 Genotype distribution and allele frequency of polymorphism in patients with chronic ITP and healthy controls

IFN-γ

Genotype

TT

3 (2.4)

2 (1)

0.38

2.44

0.40–14.80

Recessive

TA

15 (11.9)

44 (21.8)

AA

108 (85.7)

156 (77.2)

0.06

1.77

0.97–3.22

Dominant

Alleles

T

21 (8.3)

48 (11.9)

0.15

0.67

0.39–1.16

A

231 (91.7)

356 (88.1)

1.48

0.87–2.54

FN-γR

Genotypes

GG

0 (0)

0 (0)

-

-

-

GA

11 (8.7)

22 (10.9)

AA

115 (91.3)

180 (89.1)

0.53

1.28

0.60–2.73

Dominant

Alleles

G

11 (4.4)

22 (5.4)

0.54

0.79

0.38–1.66

A

241 (95.6)

382 (94.6)

1.26

0.60–2.65

IL-4

Genotypes

CC

17 (13.5)

17 (8.4)

0.14

1.70

0.83–3.46

Recessive

CT

56 (44.4)

88 (43.6)

TT

53 (42.1)

97 (48.0)

0.29

0.79

0.50–1.23

Dominant

Alleles

C

90 (35.7)

122 (30.2)

0.14

1.28

0.92–1.79

T

162 (64.3)

282 (69.8)

0.78

0.56–1.09

IL-4Rα

Genotypes

QQ

88 (69.8)

161 (79.7)

0.04

0.59

0.35–0.98

Dominant

QR

37 (29.4)

37 (18.3)

RR

1 (0.8)

4 (2.0)

0.65

0.40

0.04–3.58

Recessive

Alleles

Q

213 (84.5)

359 (88.9)

0.11

0.69

0.43–1.09

R

39 (15.5)

45 (11.1)

1.46

0.92–2.32