Fig. 6

Functional analysis of the “green” module genes. Over-represented GO/pathway terms were grouped based on kappa statistics [62]. The size of each category within a pie chart represents the number of included terms. Only the most significant GO/ terms within groups were labeled. GO/pathway terms are represented as nodes, and the node size represents the term enrichment significance, while the edges represent significant similarity between categories. a Representative biological processes interactions among module genes. b Representative molecular function interactions among module genes. c Representative Reactome analysis interactions among module genes