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Table 4 Summary of effects of specific PTMs on HLA A*02:01 binding capacity

From: Low HLA binding of diabetes-associated CD8+ T-cell epitopes is increased by post translational modifications

 

Epitopes

Non-epitopes

Total

Modification

n

% improved

n

% improved

n

% improved

Chlorination

3

66.7

26

7.7

29

13.8

Citrullination

5

40.0

65

10.8

70

12.9

Deamidation

0

16

6.3

16

6.3

Oxidation

7

0.0

59

6.8

66

6.1

Total

15

26.7

166

8.4

181

9.9