Skip to main content
Fig. 3 | BMC Immunology

Fig. 3

From: Mutant glucocorticoid receptor binding elements on the interleukin-6 promoter regulate dexamethasone effects

Fig. 3

Mutation of putative GR2 binding site reduces the basal promoter activity of IL-6 gene. Upper reveals the mutant sequences of the five GR binding sites. Lower reveals the promoter activities of mutant GR sites. Among these, the mutant GR2 binding site revealed a significant decrease than the other mutant binding sites. All values are expressed as the mean ± SD and each experiment was conducted with triplicate cultures. The intergroup comparisons were performed using Student’s two-tailed unpaired t-test

Back to article page

BMC Immunology

ISSN: 1471-2172

Contact us