Table 1 Significant GAGE pathways
From: Predicting the allergenicity of legume proteins using a PBMC gene expression assay
Treatment | Soybean (50 μg/mL) | White bean (50 μg/mL) | Soybean (50 μg/mL) |
|---|---|---|---|
Control | White bean (50 μg/mL) | control | control |
Cytokine-cytokine receptor interaction | p < 0.01 | – | p < 0.01 |
Osteoclast differentiation | p < 0.01 | – | p < 0.01 |
Neuroactive ligand-receptor interaction | p < 0.01 | – | p < 0.01 |
Hematopoietic cell lineage | p < 0.01 | – | p < 0.01 |
Rap1 signalling pathway | p < 0.01 | – | p < 0.01 |
Chemokine signalling pathway | p < 0.01 | – | p < 0.01 |
PI3K-Akt signalling pathway | p < 0.01 | – | p < 0.01 |
Complement and coagulation cascades | – | – | p < 0.01 |
Jak-STAT signalling pathway | p < 0.01 | – | p < 0.01 |
IL-17 signalling pathway | p < 0.01 | – | p < 0.01 |
PPAR signalling pathway | p < 0.01 | – | p < 0.01 |
Ovarian steroidogenesis | p < 0.01 | – | p < 0.01 |
Focal adhesion | p < 0.01 | – | – |
Protein digestion and absorption | p < 0.01 | – | – |