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Fig. 1 | BMC Immunology

Fig. 1

From: Pharmacological activation of rev-erbα suppresses LPS-induced macrophage M1 polarization and prevents pregnancy loss

Fig. 1

M1-like polarization was observed in dMφs from LPS-induced abortion model. A-B, Representative and quantitative flow cytometric analysis of the expression of M1 markers (CD11c, CD86, iNOS) and M2 marker (Arg1) in F4/80+ dMφs from normal pregnant mice and abortive mice (n = 3). C, Relative mRNA expression of pro-inflammatory cytokines (IL-1β, IL-6, TNFα, IFNγ, IL-17a) and Th2 cytokines (IL-5, TGFβ) in decidual tissue from normal pregnant mice and abortive mice (n = 6). Data showed mean ± SEM of independent experiments, **P < 0.01, ***P < 0.001

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