Skip to main content

Table 3 Cytokine production in direct contact coculture system response to TLR2 activation (pg/ml)

From: Activation of Toll-like receptor 2 enhances peripheral and tumor-infiltrating CD8+ T cell cytotoxicity in patients with gastric cancer

 

NC (peripheral) (n = 6)

GC (peripheral) (n = 17)

GC (tumor-infiltrating) (n = 17)

− Pam3Csk4

+ Pam3Csk4

− Pam3Csk4

+ Pam3Csk4

− Pam3Csk4

+ Pam3Csk4

IFN-γ

1722 ± 582.7

1810 ± 430.8

1182 ± 297.2#

1019 ± 381.1

971.6 ± 101.8 #

1001 ± 342.6

TNF-α

553.1 ± 174.5

549.7 ± 161.9

391.4 ± 87.14#

378.0 ± 92.44

360.5 ± 77.25#

371.2 ± 82.41

IL-2

221.8 ± 51.04

241.2 ± 48.16

168.4 ± 32.45#

157.9 ± 47.79

178.0 ± 45.18#

172.9 ± 34.50

IL-6

109.2 ± 23.48

105.4 ± 38.02

71.03 ± 16.46#

77.10 ± 19.24

71.42 ± 17.98#

67.14 ± 10.57

IL-8

358.0 ± 100.2

335.1 ± 109.4

234.4 ± 87.01#

221.9 ± 57.02

228.1 ± 71.03#

231.4 ± 66.02

  1. #P < 0.05 compared with NC