Figure 8From: A kinase-dead knock-in mutation in mTOR leads to early embryonic lethality and is dispensable for the immune system in heterozygous miceResponse of mTOR+/kd T cells to rapamycin. Purified T cells from spleens of mTOR+/+ and mTOR+/kd mice were cultured on anti-CD3-bound plates in the presence of various doses of rapamycin and proliferation was measured as in Fig 7. Data are expressed as % control. Results shown are representative of three experiments.Back to article page