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Figure 2 | BMC Immunology

Figure 2

From: Lactobacillus acidophilus induces a slow but more sustained chemokine and cytokine response in naïve foetal enterocytes compared to commensal Escherichia coli

Figure 2

L. acidophilus and E. coli up-regulate expression of pro-inflammatory and regulatory cytokines in foetal epithelial cells in vitro. Epithelial cells from foetuses at Day-1 were stimulated for 2 h and 4 h with LPS (10 μg/ml), L. acidophilus NCFM (10, 30 and 100 μg/ml) or E. coli Nissle (1, 10, 30 μg/ml). Gene expression was measured by RT-PCR. Symbols indicate mean fold increase and SD of 4 independent experiments with cells pooled from 6-10 pups. ***p < 0.001, **p < 0.01, *p < 0.05 compared to "unstimulated cells". Data were normalised to Actb and then to the average of "unstimulated cells 2 h" from the 4 experiments, which was defined to 1.

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BMC Immunology

ISSN: 1471-2172

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