Figure 7From: Inhibitory effects of the JAK inhibitor CP690,550 on human CD4+ T lymphocyte cytokine productionCP690,550 inhibited STATs phosphorylation in CD3 Ab-activated CD4+ T cells. CD4+ T cells were stimulated with CD3 monoclonal antibodies in the presence or absence of CP690, 550 for 24 hr and 48 hr. STAT1, STAT3, STAT4, STAT5 and STAT6 phosphorylations were measured by western blotting. The results show a representative blot from three independent experiments.Back to article page