Figure 2From: A role for the Tec family kinase ITK in regulating SEB induced Interleukin-2 production in vivo via c-jun phosphorylationITK regulates IL-2 secretion in vitro in response to SEB. Splenocytes and lymph node cells from WT (filled circles) or ITK deficient (open circles) mice were stimulated in vitro with the indicated concentrations of SEB and IL-2 levels secreted in supernatants determined. a) Time course of IL-2 secretion at 5 μg/ml SEB dose. b) IL-2 secretion over the indicated times and doses. (i) Day 1; (ii) Day 2; (iii) Day 3; (iv) Day 4 and (v) Day 5. * indicates statistically significant difference with a p < 0.05.Back to article page