Table 1 Effect of SEB on health and survival of WT and ITK null mice. Mice (WT or ITK null) were injected with the indicated amount of LPS, followed 4 hours later by 50 μg SEB, both delivered Ip. Alternatively, mice were injected with 20 mg. D-Gal and 50 μg SEB at the same time. All injections were delivered intraperitoneally. Mice were then monitored for the presence of ruffled fur, mucous in feces and lethargy. *mice had ruffled fur, mucous in feces and were lethargic. **mouse died over the course of the experiment. ***mouse had to be euthanized due to severity of sickness.

From: A role for the Tec family kinase ITK in regulating SEB induced Interleukin-2 production in vivo via c-jun phosphorylation