Skip to main content
Figure 3 | BMC Immunology

Figure 3

From: ATP-induced autophagy is associated with rapid killing of intracellular mycobacteria within human monocytes/macrophages

Figure 3

Ultrastructural appearance of infected macrophages following exposure to ATP. A. Electron micrograph of a non-ATP treated, BCG-infected macrophage showing the presence of the bacteria within phagosomes (BP). B. Exposure to ATP is associated with the appearance of numerous double-membrane autophagic vacuoles (AV) within the cell cytoplasm. C. A BCG-infected human macrophage (MDM) following treatment with 3 mM ATP for 30 minutes, the bacteria localize within autophagic vacuoles (AV) with clearly demonstrable inner (double black arrows) and outer (double white arrows) membranes. D. A higher magnification image of a number of mycobacteria contained within the inner and outer membranes of an autophagic vacuole.

Back to article page

BMC Immunology

ISSN: 1471-2172

Contact us