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Table 1 Murine immune responses to HK vaccination

From: Host immunity in the protective response to vaccination with heat-killed Burkholderia mallei

Vaccine

Pre-exposure

Post-exposure

 

IgG2a

IgG1

Ratio

IgG2a

IgG1

Ratio

HK i.n.

0.00

0.07 + .005

0.00

0.88 + .031

1.46 + .027

0.60

HK i.p.

0.01 + .012

0.23 + .015

0.04

1.04 + .037

0.92 + .0005

1.13

HK i.p. CVF

0.01 + .002

0.13 + .004

0.07

1.42 + .020

1.02 + .002

1.39

None

0.00

0.00

0.00

0.86 + .025

1.01 + .002

0.85

  1. Samples were tested in duplicate and optical densities (OD) read at 450 nm. Values are reported as mean (± S.E.M.). n = 5 for pre-exposure and n = 2 for post exposure. CVF; cobra venom factor.