Table 2 Children with suspected primary immunodeficiency disease with results of immunological analysis outside reference intervals
Study (n = 259)aNo. (%) | Excluded (n = 41)bNo. (%) | Skåneccounty No. (%) | |||
|---|---|---|---|---|---|
Immunoglobulins | IgG | 21 (8.1) | 0 | 16 (1.5) | |
IgA | 0 | 0 | 1 (0.1) | n = 1056 | |
IgM | 21 (8.1) | 0 | 37 (3.5) | ||
Immunoglobulin subclasses | IgG1 | 0 | 0 | 10 (1.0) | n = 1080 |
IgG2 | 24 (9.2) | 0 | 59 (5.4) | ||
IgG3 | 4 (1.4) | 0 | 0 | ||
IgG1 + IgG2 | 1 (0.4) | 0 | 3 (0.3) | ||
IgG1 + IgG3 | 0 | 0 | 3 (0.3) | ||
IgG2 + IgG3 | 1 (0.4) | 0 | 1 (0.1) | ||
Lymphocytes | T cells | 34 (13.1) | 5 (12.2) | 17 (4.8) | n = 348 |
T helper cells | 2 (0.7) | 0 | 1 (0.3) | ||
T cytotoxic cells | 4 (1.4) | 2 (4.8) | 0 | ||
B cells | 19 (7.3) | 1 (2.4) | 4 (1.1) | ||
NK cells | 13 (5.0) | 0 | 13 (3.7) | ||
Complement | Classical pathway | 9 (3.5) | 1 (2.4) | 26 (1.7) | n = 1473 |
Alternative pathway | 5 (1.9) | 0 | 14 (0.9) | ||
Lectin pathway | 63 (24.3) | 4 (9.6) | 26 (18.4) | n = 141 | |