Table 1 Summary of found epitopes from the study from LTNP sera
From: Identifiable biomarker and treatment development using HIV-1 long term non-progressor sera
Epitope | Epitope sequence | Location in gp160 | Sequence match |
|---|---|---|---|
A | QARLLLSGIVQQQMNLLRAT | Start: AA 541 | 100% identical (100 out of 100) |
End: AA 560 | |||
B | GCSGKLICTTTVPWNASWSNKSL | Start: AA 598 | 95.7-100% identical (20 of 100, 100%; 75 of 100, 95.7%); core epitope KLIC is 100% |
End: AA 620 | |||
C | LLELDKWASLWNWFDITNWLW | Start: AA 661 | 100% identical (100 out of 100) |
End: AA 681 | |||
D | DITNWLWYIKI | Start: AA 675 | 100% identical (100 out of 100) |
End: AA 685 | |||
E | WYIKIFIMIVGGLVGLRIVF | Start: AA 681 | 90-100% identical (3 of 100, 90%; 82 of 100, 95%; 15 of 100, 100%) |
End: AA 700 | |||
F | PEGIEEEGGERDRDTRGRLV | Start: AA 731 | 85-100% identical (8 of 100, 85%; 92 of 100, 100%) |
End: AA 750 | |||
G | IWVDLRSLFLFSYH | Start: AA 757 | 92.9-100% identical (2 of 100, 92.9%; 98 of 100, 100%) |
End: AA 770 | |||
CL3 | GCSGKLICTT | Start: AA 598 | 100% identical (100 out of 100) |
End: AA 607 |