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Fig. 5 | BMC Immunology

Fig. 5

From: Clarithromycin and dexamethasone show similar anti-inflammatory effects on distinct phenotypic chronic rhinosinusitis: an explant model study

Fig. 5

The effect of dexamethasone and clarithromycin on the production of pro-inflammatory cytokines. The protein levels of (a) granulocyte-macrophage colony stimulating factor (GM-CSF), (b) interleukin (IL)-1β, (c) IL-6, and (d) tumor necrosis factor-α (TNF-α) in culture supernatants from different phenotypic chronic rhinosinusitis after 24-h culture with 10−5 mol/L of dexamethasone or clarithromycin. An equivalent volume of methanol solution was used as control for dexamethasone and clarithromycin. CRSsNP, chronic rhinosinusitis without nasal polyps; Non-Eos CRSwNP, non-eosinophilic chronic rhinosinusitis with nasal polyps; Eos CRSwNP, eosinophilic chronic rhinosinusitis with nasal polyps; CLA, clarithromycin; CON, control; DEX, dexamethasone. n = 5 for CRSsNP group; n = 6 for Eos and Non-Eos CRSwNP group. *P < 0.05

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BMC Immunology

ISSN: 1471-2172

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