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Fig. 7 | BMC Immunology

Fig. 7

From: Clarithromycin and dexamethasone show similar anti-inflammatory effects on distinct phenotypic chronic rhinosinusitis: an explant model study

Fig. 7

The effect of dexamethasone and clarithromycin on the expression of dendritic cell relevant markers. The mRNA expression of (a) CD80, (b) CD86, (c) inducible costimulator ligand (ICOSL), (d) OX40 ligand (OX40L), and (e) programmed cell death ligand 1 (PD-L1) in sinonasal mucosa from different phenotypic chronic rhinosinusitis after 24-h culture with 10−5 mol/L of dexamethasone or clarithromycin. An equivalent volume of methanol solution was used as control for dexamethasone and clarithromycin. CRSsNP, chronic rhinosinusitis without nasal polyps; Non-Eos CRSwNP, non-eosinophilic chronic rhinosinusitis with nasal polyps; Eos CRSwNP, eosinophilic chronic rhinosinusitis with nasal polyps; CLA, clarithromycin; CON, control; DEX, dexamethasone. n = 5 for CRSsNP group; n = 6 for Eos and Non-Eos CRSwNP group. *P < 0.05

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BMC Immunology

ISSN: 1471-2172

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