Fig. 3
From: Interference with KCTD9 inhibits NK cell activation and ameliorates fulminant liver failure in mice
Increased survival in mice of mKCTD9 interference. a Schematic view of hydrodynamic delivery of plasmid and tissue collection. Individual plasmid were injected into mice with 200 μg plasmid in 200 μl saline by tail-vein injection at 24 h before and after MHV-3 infection. 20 PFU of MHV3 were injected intraperitoneally in each mice. Tissues were collected at indicated time point specifically at 24, 48 and 72 h post MHV3 infection. b Time of infected mice which were injected with pMSCV-mKCTD9-shRNA1, pMSCV-mKCTD9-shRNA2, pcDNA3.1-mKCTD9, Negative Control plasmid and saline, was calculated until death. Eighteen mice were pooled together in each cohort