Fig. 2From: Progranulin inhibits LPS-induced macrophage M1 polarization via NF-кB and MAPK pathwaysEffects of PGRN on RAW264.7 viability. a-c The effect of 5, 10, 20, 40, 80,160 and 320 ng/ml rPGRN on RAW264.7 cells was detected by CCK-8 assay after treatment for 24 h (a), 48 h (b) and 72 h (c). The optical density was normalized to a relative value of 100% for untreated cells. d Cell proliferation curve. N = 3, P < 0.05 (*), P < 0.01 (**) or P < 0.001 (***)Back to article page