Fig. 2

CD107a expression and IFN-γ production in Tim-3^−/+ CD4⁺ T and Tim-3^−/+ NK cells. a Representative flow cytometry plots of CD107a and IFN-γ levels in CD4⁺ T and NK cells. b–c CD107a expression and IFN-γ production in Tim-3^−/+ CD4⁺ T cells from HIV⁺ subjects (n = 28). d–e CD107a expression and IFN-γ production in Tim-3^−/+ NK cells in HIV⁻ (n = 13) and HIV⁺ (n = 28) subjects. All data analyzed using FacsDiva™ 8.0.3 (URL: www.bdbiosciences.com) and FlowJo™ 10.5.0 (URL: www.flowjo.com/flowjo-eula/). A Wilcoxon matched-pairs signed rank test (GraphPad Prism 9.0, URL: www.graphpad.com) was used to compare groups; ^*p < 0.05, ^**p < 0.01, ^***p < 0.001, ^****p < 0.0001