Fig. 5From: Optimizing interleukin-2 concentration, seeding density and bead-to-cell ratio of T-cell expansion for adoptive immunotherapyThe fold expansion (a, c, e) and CPD (b, d, f) results of the three donors on day 28. Twenty international units per milliliter produced the lowest number of T cells, while the difference between 50 and 100 IU/mL was not significant (a, b). All samples experienced peak expansion in 250 × 103 cell/mL (c, d). 2:1 B:C ratio results were lower than the other two, and while 10:1 increased expansion more than 5:1, the difference was not significant (e, f)Back to article page