Parasite | Parasite product | T cells polarization | Reference |
|---|
Schistosoma japonicum | rSjcystatin | ↑ CD4+ CD25+ FOXP3+ Treg | [13] |
Schistosoma japonicum | rSj16 | ↑ CD4+ CD25+ FOXP3+ Treg | [25] |
Ancylostoma caninum | AIP-1 and AIP-1Q119 | ↑ CD4+ CD25+ FOXP3+ Treg | [27] |
Trichinella spiralis | NBL-SP | ↑ CD4+ CD25+ FOXP3+ Treg | [32] |
Trichinella spiralis | TsKaSPI, TsAdSPI | ↑ CD4+ CD25+ FOXP3+ Treg | [33] |
Trichinella spiralis | rTsPmy | ↑ CD4+ CD25+ FOXP3+ Treg | [34] |
Clonorchis sinensis | CsStefin-1 | ↑ CD4+ CD25+ FOXP3+ Treg | [35] |
- Abbreviations ND: Not detected, ↑ increase, ↓ decrease. rBmCys (Brugia malayi recombinant cystatin), rWbL2 (Wuchereria bancrofti larval recombinant protein), P28GST (Schistosome 28-kDa glutathione S-transferase), rSjcystatin (Schistosoma japonicum recombinant cystatin), rSj16 (S. japonicum recombinant 16-kDa secreted protein), (AIP)-1(Ancylostoma caninum recombinant protein anti-inflammatory protein-1), AIP-1Q119 (the mutant recombinant protein AIP-1), Na-AIP-1 (Necator americanus Netrin domain-containing proteins), Nak1 (N.americanus low-MW peptide found in the excretory/secretory proteins), Acan1 (A. caninum low-MW peptides (↑4 kDa each) found in the excretory/secretory proteins), rAl-CPI (Ascaris lumbricoides recombinant cystatin protease), rTsP53 (Trichinella spiralis recombinant 53-kDa protein), NBL-SP (T. spiralis newborn larvae recombinant serine protease), TsKaSPI (T. spiralis Kazal-type serine protease inhibitors recombinant protein ), TsAdSPI (T. spiralis adult serine protease inhibitors recombinant protein), rTsPmy (T. spiralis paramyosin recombinant protein), CsStefin-1 (Clonorchis sinensis Type I cystatin recombinant protein)
